Among inflationary concerns and global semiconductor shortage, Asian stock exchange markets closed Tuesday with losses and all European major markets were in negative territory.
The Asia Dow, which includes blue-chip companies in the region, lost 33.33 points, or 0.86%, to close at nearly 3,858 points.
Tokyo's Nikkei 225 stock exchange also decreased 267.6 points, or 0.94%, to 28,230. The Hang Seng, the benchmark for blue-chip stocks trading on the Hong Kong stock exchange, saw a decrease of 362.5 points, or 1.43%, to 24,962.
China's Shanghai stock exchange was down by 44.77 points or 1.25% to reach almost 3,547 points and the Singapore index dropped by 0.09 points, or 2.8%, to reach 3,110.
Only the Indian Sensex benchmark saw an increase of 112.7 points, or 0.19%, to reach 60,248 points.
On the European side, all major indices posted negative figures during the second transaction day of the week.
The STOXX Europe 600, which includes around 90% of the market capitalization of the European market in 17 countries, was down by 1.27 points, or 0.28%, to 456.3 as of 1028GMT.
London's FTSE 100 decreased 42.7 points, or 0.6%, to 7,104, and Germany's DAX index reached 15,129 points, down by 69.7 points or 0.46%.
The French CAC 40 lost 35.5 points, or 0.54%, to 6,535 points, while Italy's FTSE MIB posted a drop of 77.1 points, or 0.3%, to 25,853 points.
Spain's IBEX 35 also dropped 13.6 points, or 0.15%, to 8,885 points.